We are seeking a postdoctoral fellow to study endogenous mechanisms that protect auditory neurons from noise-induced damage and aging. Spiral ganglion neurons (SGNs), housed in the cochlea, communicate sound information from hair cells to the central nervous system. With exposure to excess noise or with time, the synaptic connections between hair cells and SGNs are lost. In this project, we are characterizing a molecular pathway that maintains these connections and exploring its potential for the development of therapeutics. Successful applicants will have strengths in immunohistochemistry, biochemistry and/or molecular biology, with expertise in cell biology and an interest in drug discovery and translational research. Experience in the auditory system is not necessary, but a firm foundation in mechanisms of cell damage and degeneration is a plus. Our laboratory offers a welcoming and collaborative environment that places a high priority on professional training and development. Please send CV, statement of research interest, and contact information for three references to Lisa_Goodrich@hms.harvard.edu.